Sangano resainzi rakasimbisa kufa kwekutanga kunokonzerwa nealpha-gal syndromeKusawirirana nenyama yemammalian kunokonzerwa nekurumwa nezvikwekwe. Mhosva iyi, yakaferefetwa kwemwedzi yakawanda uye yakaburitswa pachena nenyanzvi kubva kuYunivhesiti yeVirginia, zvakare inoisa pachena hazvizivikanwi asi zvingangove zvakakomba mamiriro ezvinhu.
Sekureva kwemushumo wekiriniki, munhu akabatwa aive murume ane makore makumi mana nemanomwe Akava nechirwere chinouraya maawa mushure mekudya nyama tsvukuZvakawanikwa, zvakaongororwa nenyanzvi uye zvakaburitswa mu Journal of Allergy uye Clinical Immunology: Mukuita, ratidza mazinga eropa anowirirana anaphylaxis yakaoma uye kunyatsonzwa kune alpha-gal, iyo molecule yeshuga inowanikwa mumhuka dzakawanda dzinoyamwisa.
Chii chaitika
Ongororo iyi inovakazve zvikamu zviviri zvakakosha: chekutanga, panguva yerwendo rwemhuri kumisasa, mushure mekudya kwemanheru Nyama yemombe iyi yairwadziwa zvakanyanya nemudumbu, manyoka, nekurutsa. pakati pousiku; akaita nani pasina kurapwa. Masvondo gare gare, akadya hamburger masikati uye, anenge maawa mana gare gareAkawanikwa achifenda muimba yekugezera.
Yekutanga autopsy yakaronga nyaya yacho se kufa kamwe kamwe pasina chikonzero chiri pachenaAsi ongororo yakazotevera yemasampuli eropa yakaratidza zvirevo zviviri zvinogutsa: mazinga akanyanya etryptase, anowirirana Anaphylactic kuvhunduka, uye masoja ekudzivirira chirwere eIgE anorwisa alpha-gal.
Mhuri iyi yakashuma kuti murume uyu haayeuke kurumwa kwechikwekwe nguva pfupi yadarika, kunyangwe zvakadaro akanga aita maronda ekuvava gumi nemaviri pamakumbo anonzi "mites" muzhizha. Nyanzvi dzinoti, kumabvazuva kweUS, Iwo ma marks anowanzova makonye eimwe star chikwekwe. (Amblyomma americanum), mhando huru yakabatana nealpha-gal syndrome.
Vatsvagiri vanosimbisa kuti zvimwe zvinhu zvinogona kunge zvakawedzera mamiriro acho: kuita muviri mushure mekudya uye kunwiwa kwedoro, zvinhu zviviri zvinowedzera kubatwa kwealeji uye zvinogona kukonzeresa kuita kwakanyanya.
Nyaya yacho yakasimbiswa naallergist Thomas Platts-Mills, chiremera chepasi rose pamusoro pechirwere, uyo akabatanidza bvunzo dzeserological uye akanyora pamwe bhuku racho nechikwata kubva kuYunivhesiti yeVirginia.
Chii chinonzi alpha-gal syndrome?
Alpha-gal syndrome (AGS) ndeye IgE-mediated allergy iyo inogadziriswa mushure mekurumwa kwechikwekwe uye inokurudzira immune system kune alpha-gal, oligosaccharide iripo munyama ye Nyama yemombe, nguruve, gwayana, mhuka nezvimwe zvinhu zvinoyamwisa.
Chimwe chinhu chinoita kuti chiomese kuonekwa kwayo ndeye kunonoka zviratidzoZviratidzo zvinowanzoonekwa pakati pe2 ne6 maawa mushure mekudya chikafu, kusiyana nekuwanda kwekudya kwekudya, izvo zvinopinda mumaminitsi.
Mamiriro acho anotangira kubva kunyoro kusvika kune yakaoma: kuda kurutsa, dumbu remudumbu, manyoka, mikoko kana kutadza kufema. Mikoko inogona kuenderana nezvinokonzeresa zvakasiyana (consult zvokudya zvinokonzera mikoko) uye, mune mamwe mamiriro ezvinhu, iyo WMS inogona kushanduka ichipinda upenyu hunotyisa anaphylaxis kana isina kurapwa nekukurumidza.
Kunze kwenyama, vamwe vanhu vanogamuchira zvigadzirwa zvemukaka zvine mafuta akawanda (zvakadai seaizikirimu kana milkshakes) uye gelatins yemammalian mavambo, izvo zvinoda kunyatsoongororwa kwekudya (ona Zvokudya zvinokurudzirwa kuderedza histamine mazinga).
MuUnited States, zviitiko zvakawanda zvinosanganiswa ne lone star chikwekwevane kufambira mberi kwenzvimbo kwakabatana nekukura kwemhara uye munguva yechando inodziya.
Ndiani ari panjodzi uye kuti angazviziva sei
Kunyanya kuratidzwa kunoitika kune vanhu vane hupenyu hwekunze (kufamba, kuvhima, kurima) uye zvinogonawo kukanganisa vanaNekudaro, kuyedzwa hakuna basa kunze kwekunge zviratidzo zvichionekwa mushure mekudya zvigadzirwa zvemammalian.
Nyanzvi dzinokurudzira kutarisa zviratidzo zvakadai se kusagadzikana kwemudumbu, kukwenya kweganda, kana mikoko izvo zvinoonekwa maawa akawanda mushure mekudya nyama tsvuku kana mafuta emukaka. Kana vakapindirana nenhoroondo yekurumwa nekwekwe, Zvinokurudzirwa kubvunza kune alpha-gal IgE bvunzo (uye ongorora sei sarudza zvokudya zvisina zvinogumbura kune digestive system).
Pane dambudziko rakakosha reruzivo: maererano ne2023 CDC report, iyo 42% yevanachiremba vakanga vasina kunzwa nezvazvo yesyndrome, uye 35% vakabvuma kuvimba kushoma mukuongorora kana kuchirapa, izvo zvinobatsira underdiagnosis.
Vakuru vehutano veUS vanofungidzira izvozvo mazana ezviuru zvevanhu Vanogona kunge vakakanganisika kubva 2010, nekusangana munzvimbo dzinotangwa chikwekwe, kunyangwe iyo pateni iri. kuwedzera.
Sensitization inogona kudzikira nekufamba kwenguva kana... kudzivirira kumwe kurumaUye kune varwere vanovandudza mushure memakore akati wandei, asi kosi yacho inochinja uye inoda kutevera.
Kuongororwa uye kliniki nzira
Kuongororwa kunobva pane nhoroondo yezvokurapa inowirirana (kunonoka kuita mushure mekudya zvigadzirwa zvemammalian) uye murabhoritari bvunzo yekuona IgE maringe nealpha-galMuzvikamu zvakakomba, zviratidzo zvakadai se tryptase zvinotsigira kuongororwa kweanaphylaxis.
Nheyo yekona yekurapa ndiyo kunzvenga zvakasimba yenyama yemammalian uye yakakwira-njodzi inobuda (migumisiro yekurega nyama), nedzidzo yezvekudya uye kunyatsoverenga label; vamwe varwere vanodawo adrenaline auto-injector kana anaphylaxis ikaitika.
Nyanzvi dzinoti doro uye kurovedza muviri Zvinhu zviri pedyo nenguva yekudya zvinogona kuwedzera maitiro. Kuziva uye kuderedza aya macofactor kunobatsira kuderedza ngozi yezvikamu zvakakomba.
Kubva pakuona kwekutarisira, mapoka emakiriniki anofanira fungidzira SGA kana paine marwadzo makuru emudumbu, mikoko, kana zviratidzo zve systemic zvinoputika maawa akawanda mushure mekudya nyama tsvuku, kunyanya muvarwere vanobatwa nezvikwekwe.
Vanyori venyaya vanokurudzira kusimbisa iyo kudzidziswa kwenyanzvi uye kutaurirana nehuwandu hwevanhu, zvichipiwa maitiro ekukwira mukusangana nazvo kushanduka kwemamiriro ekunze uye mamiriro ekunze.
Kudzivirira uye mamiriro muSpain neEurope
Chiyero chinonyanya kushanda ndechekudzivirira kurumwa nezvikwekwe: kushandisa mishonga inodzingaZvipfeko zvenguva refu zvine mavara akajeka mumunda, bhurugwa rakaiswa mumasokisi, uye kunyatsoongorora ganda mushure mekuita zvekunze.
Kana chikwekwe chikaonekwa chakabatanidzwa, zvinokurudzirwa kuchibvisa. nekukurumidza sezvinobvira nema tweezers akanakaKudhonza zvinyoronyoro pasina kumonyorora uye kuchenesa nzvimbo; zvinokurudzirwa kucherechedza zuva uye kutarisa kwekuonekwa kwezviratidzo mumavhiki anotevera.
Kunyange zvazvo nyaya yakaongororwa inobva kuU.SA, iyo alpha-gal syndrome Yakatsanangurwawo muEurope.MuSpain, nekuvapo kwemarudzi akasiyana ezvikwekwe munzvimbo dzekumaruwa uye kunharaunda yedhorobha, kurudziro yekudzivirira uye kukurumidza kubvunza Izvo zvinoshanda zvakaenzana kune zviratidzo zvinoenderana.
Kuwedzera kwezvikwekwe kune latitude itsva kune hukama ne kunotonhora zvikuru uye kuchinja kwemhuka dzesango, ndosaka zviremera uye nzanga dzesainzi dziri kubvunza kuwedzera kuongorora uye kuziva.
Kusimbiswa kwekufa kwekutanga kubva kuGAS kunosimbisa kukosha kwe ziva maitiro ezviratidzo zvinononoka, ongorora zvichangobva kuitika zvikwekwe uye uvandudze kudzidziswa kwekiriniki ye dzivisa migumisiro yakakomba mune allergies iyo iri atypical sezvo isingakosheswi.
